Evaluation of Small Group Discussion as a Teaching- Learning Method in Biochemistry for First Year MBBS Students: A Pilot Study.

Background: Significance of Small Group Discussion as a teaching learning method is yet to be explored in teaching Biochemistry for medical students in India. Hence, this experimental pilot study was undertaken to assess the effectiveness of small group discussion for first year MBBS students in learning Biochemistry. Materials and Methods: A voluntary group of 40 first year MBBS students were chosen randomly for the study comprising of both high achievers and low achievers. Study was conducted on a particular day for five consecutive weeks. In each session, small group discussion study pattern included a pretest followed by group discussion then by a post-test. Participants‘ feedback was obtained after completion of the study. Statistical comparisons were done on each PAIR (pre-test and post-test) of Mean scores obtained and Pearson‘s correlation co-efficient were calculated for each pair. Statistical significance was obtained at p<0.05. Results: Mean post-test scores were increased compared to mean pre-test scores in each PAIR and the increase was statistically significant. Significant positive correlations were observed between pretest scores and post-test scores in all PAIRS. Majority of the study group felt that small group discussion method will enhance their learning and memory. Conclusion: This pilot study emphasizes that small group teaching is an effective teaching learning method to develop the student‘s critical thinking and problem-solving skills. However, larger studies at several medical colleges for a longer duration have to be undertaken before arriving at a conclusion.

Lipid peroxidation and total antioxidant capacity in health and disease - Pathophysiology and markers: An overview.

Free radicals play a significant role in the pathogenesis of many chronic diseases such as diabetes mellitus, cancer, chronic renal failure etc. Oxidative stress is defined as “a disturbance in the balance between the antioxidants and pro-oxidants (OFR in particular) with increased levels of pro-oxidants leading to potential damage. The knowledge about pathophysiology of lipid peroxidation and the oxidative stress biomarkers will definitely help the researchers to plan for focused study for better management of oxidative stress induced diseases.